Publications (PubMed)

  • Feng Q, Jagannathan S, Bradley RK. The RNA Surveillance Factor UPF1 Represses Myogenesis via Its E3 Ubiquitin Ligase Activity. Molecular cell. 2017; 67(2):239-251.e6. Link

  • Jagannathan S and Bradley RK. Congenital myotonic dystrophy-an RNA-mediated disease across a developmental continuum. Genes & development. 2017; 31(11):1067-1068. Link

  • Shadle SC, Zhong JW, Campbell AE, Conerly ML, Jagannathan S, Wong CJ, Morello TD, van der Maarel SM, Tapscott SJ. DUX4-induced dsRNA and MYC mRNA stabilization activate apoptotic pathways in human cell models of facioscapulohumeral dystrophy. PLoS genetics. 2017; 13(3):e1006658. Link

  • Jagannathan S and Bradley R. Translational plasticity facilitates the accumulation of nonsense genetic variants in the human population. Genome Research2016 Sep 19. doi:10.1101/gr.205070.116. Link bioRxiv

  • Jagannathan S* , Shadle SC*, Resnick R, Snider L, Tawil RN, van der Maarel SM, Bradley RK and Tapscott SJ. Model systems of DUX4 expression recapitulate the transcriptional profile of FSHD cells. Hum Mol Genet. 2016 Aug 15. (*Equal Contribution) Link

  • Feng Q, Snider L, Jagannathan S, Tawil R, van der Maarel SM, Tapscott SJ, Bradley RK. A feedback loop between nonsense-mediated decay and the retrogene DUX4 in facioscapulohumeral muscular dystrophy. Elife. 2015 Jan 7;4. Link

  • Jagannathan S, Reid DW, Cox AH, Nicchitta CV. De novo translation initiation on membrane-bound ribosomes as a mechanism for localization of cytosolic protein mRNAs to the endoplasmic reticulum. RNA. 2014 Oct; 20(10):1489-98. Link

  • Jagannathan S* , Hsu JC*, Reid DW, Chen Q, Thompson WJ, Moseley AM, Nicchitta CV. Multifunctional roles for the protein translocation machinery in RNA anchoring to the endoplasmic reticulum. J Biol Chem. 2014 Sep 12; 289(37):25907-24. (*Equal Contribution) Link

  • Lacsina JR, Marks OA, Liu X, Reid DW, Jagannathan S, Nicchitta CV. Premature translational termination products are rapidly degraded substrates for MHC class I presentation. PLoS One. 2012; 7(12):e51968. Link

  • Chen Q, Jagannathan S*, Reid DW, Zheng T, Nicchitta CV. Hierarchical regulation of mRNA partitioning between the cytoplasm and the endoplasmic reticulum of mammalian cells. Mol Biol Cell. 2011 Jul 15; 22(14):2646-58. (*Equal Contribution) Link

  • Jagannathan S, Nwosu C, Nicchitta CV. Analyzing mRNA localization to the endoplasmic reticulum via cell fractionation. Methods Mol Biol. 2011; 714:301-21. Link